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G-Protein Genomic Association With Normal Variation in Gray Matter Density
SNP sMRI multivariate semi-blind G-protein
2015/12/18
While detecting genetic variations underlying brain structures helps reveal mechanisms of
neural disorders, high data dimensionality poses a major challenge for imaging genomic association
studies. ...
Exploring the Boundaries:Gene and Protein Identification in Biomedical Text
Gene and Protein Identification Biomedical Text
2015/6/12
We present a maximum-entropy based system incorporating a diverse set of features for identifying genes and proteins in biomedical abstracts. This system was entered in the BioCreative comparative eva...
Exploring the boundaries:gene and protein identification in biomedical text
Exploring the boundaries gene and protein biomedical text
2015/6/12
Background: Good automatic information extraction tools offer hope for automatic processing of the exploding biomedical literature, and successful named entity recognition is a key component for such ...
De novo TBR1 mutations in sporadic autism disrupt protein functions
TBR1 mutations sporadic autism disrupt protein functions
2015/5/5
Next-generation sequencing recently revealed that recurrent disruptive mutations in a few genes may account for 1% of sporadic autism cases. Coupling these novel genetic data to empirical assays of pr...
Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer
Protein-protein Interactions Live Cells Bioluminescence Resonance Energy Transfer
2015/5/5
Assays based on Bioluminescence Resonance Energy Transfer (BRET) provide a sensitive and reliable means to monitor protein-protein interactions in live cells. BRET is the non-radiative transfer of ene...
Computational identification of new structured cis-regulatory elements in the 30-untranslated region of human protein coding genes
Computational identification cis-regulatory elements the 30-untranslated region human protein coding genes
2015/4/20
Messenger ribonucleic acids (RNAs) contain a large number of cis-regulatory RNA elements that function in many types of post-transcriptional regulation. These cis-regulatory elements are often charact...