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米糠蛋白ACE抑制肽在大鼠体内降压效果的研究
米糠蛋白ACE抑制肽 SHR大鼠 降血压
2016/5/20
采用灌胃和静脉注射的方法,观察了米糠蛋白ACE抑制肽对应激性高血压(SHR)大鼠的降压效果,并与卡托普利的降压效果进行了比较。分别以50、100、150 mg/kg·bw剂量的米糠蛋白ACE抑制肽一次性给药后,每2 h测量大鼠血压,连续测量8 h;实验持续4周,每天灌胃一次,每周测量血压及体重一次。SHR大鼠给予米糠蛋白ACE抑制肽后,血压均显著下降(p0.05),并均在灌胃后2 h达到最低值,血...
目的:为了建立定量检测酪蛋白水解物中的血管紧张素转换酶(ACE)抑制肽的反相高效液相色谱(RP-HPLC)方法。方法:酪蛋白先经过胃蛋白酶水解、再经过胰蛋白酶水解,用风味蛋白酶和离子交换树脂对水解物先后进行脱苦和脱盐处理。建立标准品十肽酪氨酸-谷氨酰胺-赖氨酸-苯丙氨酸-脯氨酸-谷氨酰胺-酪氨酸-亮氨酸-谷氨酰胺-酪氨酸(YQKFPQYLQY)的RP-HPLC检测方法,运用外标法测定酪蛋白水解物中...
A New Probiotic Cheddar Cheese with High ACE-Inhibitory Activity and γ-Aminobutyric Acid Content Produced with Koumiss-Derived Lactobacillus casei Zhang
ACE-inhibitory activity Lactobacillus casei Zhang g-aminobutyric acid koumiss
2010/8/11
Cheddar cheese has been manufactured with Lactobacillus casei Zhang as the dairy starter adjunct. L. casei Zhang had previously been isolated from koumiss collected from Xilin Guole in Inner Mongolia ...
Animal and Plant Proteins as Precursors of Peptides with ACE Inhibitory Activity – An in silico Strategy of Protein Evaluation
proteins ACE inhibitors BIOPEP database in silico methods biological activity functional food
2010/3/24
This paper presents a modern in silico approach useful in the evaluation of proteins as a source of ACE inhibitors. All protein sequences analyzed were derived from the BIOPEP database. To determine t...