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Genetic and environmental factors of atopy
allergy asthma atopy FcεRIγ interleukin-4 interleukin-13 Th1 Th2 imbalance
2010/11/24
Atopy is a common immune disorder characterized by raised IgE levels, which lead to clinical disorders (i.e. primarily bronchial asthma, atopic dermatitis and allergic rhinoconjuctivitis). Interleukin...
Genetic defects in downregulation of IgE production and a new genetic classification of atopy
atopy IgE production downregulation interferon-γ interleukin-12 receptor β2 interleukin-18 receptor α
2010/11/22
Atopic disorders, such as asthma, eczema and rhinitis, develop due to the interactions between genetic and environmental factors. Atopy is characterized by enhanced IgE responses to environmental anti...
A Study of Relation between BCG Scar and Atopy in Schoolchildren of Zanjan City
Allergy Asthma BCG vaccine Dermatitis Atopic
2010/2/8
The prevalence of atopic disease in recent decades has been dramatically increased. It has been suggested that BCG vaccination may protect against development of allergic diseases. The purpose of this...
Environmental Exposure to Endotoxin and Decreased Risk of Childhood Atopy
asthma atopy endotoxin hygiene hypothesis metropolitan environment
2010/11/19
The hygiene hypothesis implies, in immunological terms, that microbial stimulation in early life skews the immune system towards the development of a T helper type 1 (Th1)-type lymphocyte population, ...