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Contribution of K+ Channels to Coronary Dysfunction in Metabolic Syndrome
obesity ion channels metabolic syndrome blood flow
2015/5/22
Coronary microvascular function is markedly impaired by the onset of the metabolic syndrome and may be an important contributor to the increased cardiovascular events associated with this mutlifactori...
Role of KATP Channels in Beneficial Effects of Exercise in Ischemic Heart Failure
CHRONIC HEART FAILURE ATP-SENSITIVE POTASSIUM CHANNELS GLIBENCLAMIDE CHRONIC EXERCISE CALCIUM CELL SURVIVAL
2017/4/20
Exercise training reduces pathological remodeling and improves cardiac function in ischemic heart failure; however, causal mechanisms underlying the cardiac benefits of exercise are poorly understood....
Parathyroid Hormone Enhances Mechanically Induced Bone Formation, Possibly Involving L-Type Voltage- Sensitive Calcium Channels
parathyroid hormone bone formation
2014/12/4
PTH and mechanical loading might act synergistically on bone formation. We tested the in vivo effect of the L-type voltage-sensitive calcium channel (VSCC) blocker, verapamil, on bone formation induce...
1α,25-dihydroxyvitamin D3 Rapidly Modulates Ca2+ Influx in Osteoblasts Mediated by Ca2+ Channels
Non-genomic action 1α 25-dihydroxyvitamin D3 Osteoblasts
2011/6/10
The biologically active form of vitamin D, 1α,25-dihydroxy vitamin D3 (VD), regulates the synthesis of the bone Ca-binding proteins osteocalcin and osteopontin. The actions of VD are mediated through ...
Effects of halothane and hydrostatic pressure on sodium channels in squid axon
neurological squid animal halothane high pressure nervous syndrome
2009/7/14
The effects of halothane and hydrostatic compression have been studied on the voltage-dependent sodium conductances in the squid giant axon. Compression to 150 atmospheres reduced the time course of b...
Fabrication of Biodegradable Membrane Micro-channels for Artificial Blood Capillary Networks Using Membrane Micro Embossing (MeME)
tissue engineering blood capillary biodegradable micro-channel emboss
2009/6/9
The authors of this letter propose a novel “multi-layer hybrid scaffold” consisting of artificial blood capillary networks and cell-containing hydrogel for tissue engineering. The artificial blood cap...
Blockers of K+/Cl- transporter/channels diminish proliferation of osteoblastic cells
K+/Cl- transporter/channels osteoblastic cells
2009/5/8
In the preset report, we studied if blockers of the K+/Cl- cotransporter, and Cl- and K+ channels modify the proliferation of MC3T3-E1 osteoblastic cells. A blocker of the K+/Cl- cotransporter, DIOA...
Regulation of volume-regulated outwardly rectifying anion channels by phosphatidylinositol 3,4,5-trisphosphate in mouse ventricular cells
phosphatidylinositol 3,4,5-trisphosphate mouse ventricular cells
2009/3/2
Volume-regulated outwardly rectifying anion channel (VRAC) plays an important role in cellvolume regulation in many types of cells. Little is known about the regulation of VRAC by phosphatidylinosit...
Voltage-dependent calcium channels and Gi regulatory protein mediate the human sperm acrosomal exocytosis induced by N-acetylglucosaminyl/mannosyl neoglycoproteins
Carbohydrate G-protein acrosome reaction VDCC neoglycoproteins
2009/2/16
Mammalian spermatozoa must undergo an exocytotic event during fertilization, the acrosome reaction (AR). In most species studied this process is induced by specific glycoproteins of the oocyte ext...
K Channels as Molecular Targets for the Treatment of Erectile Dysfunction
K Channels Molecular Targets Treatment Erectile Dysfunction
2008/12/15
Normal erectile function is a complex neurovascular process that is dependent on a delicate balance between the effects of endogenous vasoconstrictor and vasorelaxing agents on the arterial and corpor...
K Channels as Molecular Targets for the Treatment of Erectile Dysfunction
K Channels Molecular Targets Treatment Erectile Dysfunction
2008/12/15
Normal erectile function is a complex neurovascular process that is dependent on a delicate balance between the effects of endogenous vasoconstrictor and vasorelaxing agents on the arterial and corpor...
专著信息
书名
Regulation of Intracellular Cl- Concentration Through Volume-Regulated ClC-3 Chloride Channels in A10 Vascular Smooth Muscle Cells. J Biol Chem 280:7301-7308, 2005
语种
英文
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作者
Jia-Guo Zhou...
期刊信息
篇名
Expression of Delayed Rectifier Potassium Channels and their Possible Roles in Proliferation of Human Gastric Cancer Cells.
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英文
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作者
兰梅,时永全,韩者艺,郝志明,潘阳林,刘娜,郭长存,洪流,王钧,乔泰东,樊代明。
第一作者单位
第四...
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篇名
Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord
语种
英文
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作者
Wu LJ,Duan B,Mei YD,Gao J,Chen JG,Zhuo M,Xu L,Wu M,Xu TL
第一作者单位
刊物名称
Journal of Biologica...
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篇名
Effect of drugs on mRNA expression of voltage-gated potassium channels myocardial remodeling by charonic L-thyroxine adminstration in rats
语种
英文
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作者
Fang-Zhi Fang,Zi-Zhen Wang,De-Zai D...