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By the time unambiguous signs of memory loss and cognitive decline appear in people with Alzheimer’s disease, their brains already are significantly damaged, dotted with clumps of a destructive protei...
The aim of the present study was to evaluate the ixodicide efficacy of the experimental compound 712-BF-016 against Rhipicephalus (Boophilus) microplus ticks in vitro and in cattle. The in vitro effic...
人参皂苷Compound KCK,20-O-β-D-葡萄糖基-20(S)-原人参二醇]是原人参二醇型人参皂苷在人体内主要吸收形式和药效实体。近年来, CK的药理活性研究又有了新进展:① CK可通过活化胱天蛋白酶8直接或通过线粒体途径间接地激活胱天蛋白酶3,诱导肿瘤细胞凋亡;下调基质金属蛋白酶9基因的表达,抑制肿瘤细胞的转移;② 可通过下调多种炎症因子如白细胞介素-4(IL-4),IL-6,肿瘤坏...
筛选具有人参皂苷转化能力的真菌菌株,用于生产稀有人参皂苷compound K。 方法 :通过液态发酵,以三七茎叶总皂苷为底物,采用TLC和HPLC-ELSD检测转化产物,从12株植物病原真菌中筛选能够转化产生人参皂苷compound K的最佳菌株。 结果 :获得一株高效人参皂苷转化真菌,可以转化产生人参皂苷compound K,该菌株为镰刀属真菌串珠镰孢Fusarium moniliforme。 ...
The purpose of this study was to evaluate the effect of primers on bonding between a silver-palladium-copper-gold alloy and an indirect composite material. Cast disks were air-abraded with alumina, co...
New synthesis methods have allowed us to make many semiconducting polythiophenes polymers with different side and end groups. Also, co-polymers combining a polythiophene chain attached to another p...
Obtaining ECAP recordings is also possible in the most apical region of the cochlea. However, differences can be observed depending on the region of the cochlea stimulated. Specifically, significant h...
人参皂苷compound K是二醇型人参皂苷在人体肠道内的主要代谢产物和最终吸收形式。近年来,由于其各种出色的生物活性和作用,对该化合物的研究越来越受到重视。本文对人参皂苷compound K的制备、生物活性、吸收及代谢等研究进行了详细综述。
The purpose of this study was to evaluate the performance of modified 4-META/ MMA-TBB resin cements (Superbond C&B) in terms of debonding orthodontic brackets easily and safely from enamel without the...
The goal of this study was to perform 5--reductase type 2 gene (SRD5A2) analysis in a male pseudohermaphrodite (MPH) patient with normal testosterone (T) production and normal androgen receptor (AR)...
Objective: Patients often reach the hospital late after passage of golden hours (initial 6 hours) after sustaining high-velocity injuries. The decision of internal fixation in Gustilo's Type IIIA and ...
期刊信息 篇名 Anti-angiogenic effects of shiraiachrome A, a compound isolated from a Chinese folk medicine used to treat rheumatoid arthritis. 语种 英文 撰写或编译 撰写 作者 Tong YG.,Zhang XW.,Zhao WM.,Zhang YX.,Lang JY...
期刊信息 篇名 Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects. 语种 英文 撰写或编译 撰写 作者 Tong YG.,Zhang XW.,Tian F.,Yi YH.,Xu QZ.,Li L.,Tong LJ.,Lin LP.,Ding J...
期刊信息 篇名 11,11’-dideoxy-verticillin, a natural compound possessing growth factor receptor tyrosine kinases inhibitory effect with antitumor activity. 语种 英文 撰写或编译 撰写 作者 Zhang YX.,Chen Y.,Guo XN.,Zhang X...
Regioregular polythiophene-based conductive copolymers with highly crystalline nanostructures are shown to hold considerable promise as the active layer in volatile organic compound (VOC) chemresisto...

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