搜索结果: 1-12 共查到“临床医学 allergic diseases”相关记录12条 . 查询时间(0.048 秒)
Management of Food Allergy in Japan "Food Allergy Management Guideline 2008 (Revision from 2005) " and "Guidelines for the Treatment of Allergic Diseases in Schools"
anaphylaxis food allergy oral food challenge test referral relationship school
2010/11/16
In 2005, the "Food Allergy Management Guideline 2005" was published. In order to encompass food allergy from infancy to adulthood, the project committee included not only pediatricians, but also inter...
The Role of Leukotriene B4 in Allergic Diseases
allergic conjunctivitis allergic rhinitis asthma atopic dermatitis
2010/11/17
Leukotriene B4 (LTB4) is a lipid mediator with potent chemoattractant properties and that is rapidly generated from activated innate immune cells such as neutrophils, macrophages, and mast cells. Elev...
Targeting Human Mast Cells Expressing G-Protein-Coupled Receptors in Allergic Diseases
allergic diseases bronchial asthma GPCRs human mast cells urticaria
2010/11/17
The G-protein-coupled receptors (GPCRs) are the largest known group of integral membrane receptor proteins and are the most common targets of pharmacotherapy. Mast cells (MCs) have been reported to pl...
Invariant Natural Killer T (iNKT) Cells in Asthma: A Novel Insight into the Pathogenesis of Asthma and the Therapeutic Implication of Glycolipid Ligands for Allergic Diseases
allergic asthma glycolipid ligand invariant NKT cells Th2 cytokine T helper (Th) 2 cell α-galactosylceramide
2010/11/18
Allergic bronchial asthma is a complex inflammatory diseases originated from dysregulated immune responses in the respiratory mucosa. The inflammatory state in asthmatic lung is characterized by massi...
Role of α-Galactosylceramide-activated Vα14 Natural Killer T Cells in the Regulation of Allergic Diseases
IFN-γ IgE Th2 responses Vα14 NKT cell α-Galactosylceramide
2010/11/18
Vα14 natural killer T (NKT) cells produce large amounts of both IL-4 and IFN-γ upon stimulation with a ligend, α-galactosylceramide (α-GalCer), and play a crucial role in various immune responses, inc...
Evaluation of FcεRI-binding serum IgE in patients with ocular allergic diseases
atopic keratoconjunctivitis ELISA FcεRI FcεRI-binding IgE seasonal allergic conjunctivitis
2010/11/29
We evaluated high-affinity receptor for IgE (FcεRI)-binding serum IgE in patients with atopic kerato- conjunctivitis (AKC; n = 31) and with seasonal allergic conjunctivitis (SAC; n = 13) by enzyme-lin...
Risk factors for asthma and allergic diseases among 13-14-year-old schoolchildren in Japan
allergy asthma childhood International Study of Asthma and Allergies in Childhood prevalence risk factor
2010/11/24
In analyses of family histories, the odds ratios (OR) of children who have a family history with no symptoms were significantly lower by risk factor-based analyses compared with those children with a ...
Dinucleotide repeat polymorphisms in the signal transducers and activators of transcription 6 (Stat6) gene in children with allergic diseases
atopy dinucleotide repeat polymorphism interleukin-13 interleukin-4 signal transducers and activators of transcription 6 (Stat6)
2010/11/22
Background: Signal transducers and activators of transcription 6 (Stat6) is involved in the interleukin (IL)-4 and IL-13 signaling pathway. The aim of the present study was to evaluate whether polymor...
Role of dendritic cells in Th1/Th2 balance: A novel therapeutic target of allergic diseases
dendritic cell monocyte chemotactic protein-1 OX40 ligand regulatory T cells Th2
2010/11/22
Considerable evidence supports the role of dendritic cells (DC) in the pathogenesis of allergic diseases. Dendritic cells, as the most potent antigen-presenting cells (APC) for the induction of primar...
Questionnaire-based Study on the Relationship between Pet-keeping and Allergic Diseases in Young Children in Japan
allergy asthma atopic dermatitis cats dogs Japan pet-keeping
2010/11/22
Background: It is still unclear how early exposure to pets is related to the risk of developing atopy-related diseases in children. There are few reports on this pet-allergy relationship in Japan alth...
Effects of Probiotics on the Immune System and Allergic Diseases
adaptive immunity allergic diseases commensals epithelial cells innate immunity intestinal microbiota probiotics
2010/11/22
Intestinal microbiota play a crucial role in the development of mucosal tolerance and adaptation. Perturbations in microbiota composition are strongly associated with allergies and asthma in westerniz...
CpG Oligodeoxynucleotides as a Future Vaccine for Allergic Diseases
antigen-specific bronchial asthma dendritic cell Th1/Th2 cell
2010/11/19
An astounding feature of the DNA sequences termed CpG motifs is the induction of immune and inflammatory responses in a senseless manner. CpG motifs exist abundantly in microbes and evoke innate immun...