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Localization of the human prostatic secretory protein PSP94 and its mRNA in the epithelial cells of the prostate
man prostate protein mRNA epithelium secretion
2009/2/23
The histologic distribution of a prostatic secretory protein of 94 amino acids (PSP94) and its mRNA were examined simultaneously by conventional immunohistochemistry and in situ hybridization histoc...
Effects of short-term methylmercury exposure on metallothionein mRNA levels in the testis and epididymis of the rat
short-term methylmercury metallothionein mRNA rat
2009/2/18
Methylmercury (MeHg) is a widespread environmental contaminant that causes reproductive dysfunction in men. Metallothioneins (MTs) are low-molecular-weight proteins that can bind heavy metals and pr...
The classic testicular tumor marker alpha-fetoprotein (AFP) is associated with nonseminomatous germ cell tumors, including embryonal carcinoma, yolk sac tumor, and teratoma. AFP is not considered to...
Regional distribution of 5alpha-reductase type 1 and type 2 mRNA along the nonhuman primate (Macaca fascicularis) epididymis
Cynomolgus monkey RT-PCR gene expression
2009/2/17
The 5alpha-reduced metabolites of testosterone, including dihydrotestosterone, are considered the primary regulators of epididymal function. Two genes encode two 5alpha-reductase isozymes. We exam...
Stability and transcriptional regulation of gamma-glutamyl transpeptidase mRNA expression in the initial segment of the rat epididymis
Stability transcriptional regulation gamma-glutamyl transpeptidase mRNA initial segment rat epididymis
2009/2/17
Gamma-glutamyl transpeptidase (GGT) is an enzyme believed to play a role in the protection of maturing spermatozoa in the epididymis. Our previous studies have shown that four GGT mRNAs (I-IV) trans...
Sertoli cells in culture and mRNA differential display provide a sensitive early warning assay system to detect changes induced by xenobiotics
Sertoli cells culture mRNA differential display
2009/2/17
We have used cultured rat Sertoli cells as an "early warning system" to monitor for morphological and biochemical changes induced by two different xenobiotics-cadmium acetate and polychlorinated bip...
Characterization and developmental expression of a testis-specific adenosine deaminase mRNA in the mouse
testis-specific adenosine deaminase mRNA mouse
2009/2/17
Adenosine is able to alter intracellular cAMP levels and to affect the physiological functions of sperm. It also modulates FSH action through its Gi protein coupled receptors. Adenosine deaminase (A...
Expression of apolipoprotein E mRNA in the epithelium and interstitium of the testis and the epididymis
Apolipoprotein E mRNA Leydig cells Sertoli cells
2009/2/17
Apolipoprotein E (apo E) is an important constituent of plasma lipoproteins and is believed to be involved in the regulation of lipid transport and distribution between tissues. The production of ...
Catalase mRNA expression in the male rat reproductive tract
Catalase mRNA expression male rat
2009/2/16
Reactive oxygen species (ROS) have been shown to impair sperm function. The actions of ROS are reduced by antioxidant enzymes, including catalase. Although catalase-like activity has been demonstrated...
Purification, cDNA cloning, and developmental changes in the steady-state mRNA level of rat testicular tissue inhibitor of metalloproteases-2(TIMP-2)
Purification cDNA cloning steady-state mRNA level rat
2009/2/16
Using multiple high-performance liquid chromatography (HPLC) steps and high-performance electrophoresis chromatography (HPEC) in conjunction with an [125I]collagen film assay to identify inhibitors ...
Alteration of mRNA transcript levels of rat testicular cells following procarbazine administration
mRNA transcript levels rat testicular cells procarbazine administration
2009/2/12
The present study examined the effects of a single 400-mg/kg dose of procarbazine upon various testicular mRNA transcript levels in adult Sprague-Dawley rats. Northern blot hybridization was emplo...
Regulation of caltrin mRNA expression by androgens in the murine prostate
caltrin mRNA androgens murine prostate
2008/12/26
Testicular androgens induce the proliferation and differentiation of prostatic epithelial cells by regulating the expression of androgen target genes. The use of subtractive hybridization to isolate...
A putative messenger RNA (mRNA) sequence, designated C8, that was up-regulated in Sertoli cells prepared from hypophysectomized rats treated with testosterone, was isolated from a Sertoli cell compl...
Expression of crisp-1 mRNA splice variants in the rat epididymis, and comparative analysis of the rat and mouse crisp-1 gene regulatory regions
crisp-1 mRNA rat epididymis rat and mouse crisp-1 gene
2008/12/26
The rat Crisp-1 gene encodes Protein DE (acidic epididymal glycoprotein; AEG), a glycoprotein secreted by the epididymal epithelium that associates with maturing sperm and has been implicated in the p...
Expression of a Novel RAD23B mRNA Splice Variant in the Human Testis
RAD23 alternative splice ubiquitin spermatogenesis proteolysis self-balance
2008/12/22
A gene coding a novel human RAD23B protein named RAD23-like protein B, presumably involved in spermatogenesis, was identified and characterized using a complementary DNA (cDNA) microarray. In the hu...