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Dose and time relationships in the endocrine response of the irradiated adult rat testis
endocrine response irradiated adult rat testis
2009/2/23
The dose- and time-dependent responses for the interstitial and tubular compartments in irradiated adult rat testes are described. Leydig cell dysfunction, as indicated by increased serum LH (to a m...
Structural features of cultured epithelial cells from the adult rat epididymis
epididymis epithelium primary culture
2009/2/20
Epithelial cells isolated from the caput epididymidis of adult rats were placed in primary culture and examined daily for ten days for changes in external anatomy, reorganization of cytoskeletal com...
Cell- and region-specific localization of lysosomal and secretory proteins and endocytic receptors in epithelial cells of the cauda epididymidis and vas deferens of the adult rat
Cell- and region-specific localization secretory proteins endocytic receptors
2009/2/18
The epithelial cells lining the cauda epididymidis and vas deferens are active in endocytosis and have an abundance of lysosomes and a well-characterized secretory apparatus. However, little is kn...
Principal cells of the vas deferens are involved in water transport and steroid synthesis in the adult rat
Principal cells vas deferens water transport steroid synthesis adult rat
2009/2/18
Principal cells show marked structural differences in the proximal, middle, and distal regions of the vas deferens, reflective of diverse functional activities. In the present study, we performed el...
Androgen binding protein secretion and endocytosis by principal cells in the adult rat epididymis and during postnatal development
Androgen binding protein secretion endocytosis principal cells adult rat epididymis
2009/2/18
Androgen binding protein (ABP) has been shown to be secreted by Sertoli cells and to be actively taken up by the efferent ducts and proximal caput epididymidis and, yet, to be present at high concen...
Apoptosis pattern elicited by several apoptogenic agents on the seminiferous epithelium of the adult rat testis
Apoptosis pattern apoptogenic agents seminiferous epithelium adult rat testis
2009/2/17
Spontaneous germ cell death during spermatogenesis is an important event, and the usefulness of the seminiferous epithelium as an in vivo model to study apoptosis has been evidenced. Nevertheless, the...
Effect of chorionic gonadotropin and flutamide on Leydig cell and macrophage populations in the testosterone-estradiol-implanted adult rat
chorionic gonadotropin Leydig cell macrophage populations testosterone-estradiol-implanted adult rat
2009/2/17
The objective of this study was to investigate the role of androgens and nonandrogenic Leydig cell products in maintaining Leydig cell and macrophage numbers in the testis of the adult rat. Adult ...
The effects of gonadotropin-releasing hormone immunization and recombinant follicle-stimulating hormone on the Leydig cell and macrophage populations of the adult rat testis
Stereology morphometry optical disector leucocytes
2009/2/17
The objective of this study was to investigate the role of the gonadotropins and, in particular follicle-stimulating hormone (FSH) in maintaining the Leydig cell and macrophage populations of the adul...
Differential methylation in steroid 5 alpha-reductase isozyme genes in epididymis, testis, and liver of the adult rat
Gene methylation gene expression androgens dihydrotestosterone eukaryotic adenine methylation
2009/2/17
DNA methylation has been largely involved in the regulation of tissue-specific gene expression. The aim of the study was to determine the methylation pattern of steroid 5 alpha-reductase genes 1 and 2...
Apical and narrow cells are distinct cell types differing in their structure, distribution, and functions in the adult rat epididymis
Apical and narrow epithelial cells initial segment intermediate zone epididymis rat
2009/2/16
Apical and narrow cells of the initial segment and intermediate zone of the adult rat epididymis were glutaraldehyde fixed and Epon embedded for routine light (LM) and electron (EM) microscopic an...
Endocrine and exocrine effects of testicular torsion in the prepubertal and adult rat
testicular torsion prepubertal adult rat
2009/2/13
Previous studies of experimental torsion have suggested that there may be important differences between the adult testis and the prepubertal testis in their responses to torsion, especially with reg...
Measurement of immunoglobulin G levels in adult rat testicular interstitial fluid and serum
immunoglobulin G levels adult rat serum
2009/2/13
Total immunoglobulin G (IgG) in rat testicular interstitial fluid and serum was measured by two-site enzyme-linked immunosorbent assay, which displayed minimal cross-reactivity with IgA or IgM. Norm...
Effects of macrophage depletion at different times after treatment with ethylene dimethane sulfonate(EDS)on the regeneration of Leydig cells in the adult rat
Ethylene dimethane sulfonate Leydig cells regeneration macrophage depletion
2009/2/13
Testicular macrophages were selectively depleted in the right testes of adult rats by an intratesticular injection of dichloromethylene diphosphonate-containing liposomes (Cl2MDP-lp), whereas the le...
An investigation of the requirement for increased LH secretion during the compensatory response in androgen secretion after unilateral castration of the adult rat
Hormone implants immunoactive bioactive
2009/2/10
The endocrine mechanisms underlying the response to unilateral castration were examined by determining systemic androgen and luteinizing hormone (LH) concentrations, as well as testicular vein andro...
Effects of insulin-like growth factor-I on androgen production by highly purified pubertal and adult rat Leydig cells
Somatomedin-C development steroidogenesis
2009/2/10
Leydig cells were isolated and purified from adult and midpubertal rats to study the effects of insulin-like growth factor-I (IGF-I) on steroidogenesis. Androgen production, as measured in Leydig ce...