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无义介导的RNA降解(Nonsense-mediated decay, NMD)是真核生物一种重要的mRNA质量控制方式,细胞通过检验终止密码子与最后一个剪接接头的距离是否超过55nt来判断该终止密码子是否为提前终止密码子(Premature Termination Codon, PTC)从而决定是否降解该RNA。因此经典的NMD通路是一种RNA剪接依赖的机制。假基因是一种失去了蛋白编码能力或者表...
Heterogeneity of 3’-Untraslated Region of Genome RNA of the Tick-Borne Encephalitis Virus (TBEV) Strains Isolated from Ticks in the Western Siberia, Russia
deletions hemagglutination neurovirulence reverse transcription–polymerase chain reaction
2009/4/20
The tick-borne encephalitis virus (TBEV) strains have been isolated from unfed adult ticks Ixodes persulcatus Schulze in Novosibirsk region (South-Western Siberia, Russia) beginning from 1980 till 200...
Overlapping of Genes in the Human Genome
overlapping genes human genome locus exon chromosome
2009/4/20
Overlapping genes are relatively common in DNA and rNA viruses. there are several examples in bac-terial and eukaryotic genomes, but, in general, overlapping genes are quite rare in organisms other th...