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Successful response to imatinib in two dogs with inoperable grade III infiltrating mast cell tumours:a case report
canine KIT oncogene target therapy tyrosine kinase inhibitor
2016/9/1
Two dogs were presented owing to sudden rapid growth of cutaneous masses greater than 10 cm on the neck and axillary region, respectively. Based on history and results of physical examinations, blood ...
Chronic Myeloid Leukemia with Variant Chromosomal Translocations:Results of Treatment with Imatinib Mesylate
Chronic myeloid leukemia Imatinib Variant translocation
2015/7/10
Objective: To evaluate the efficacy of imatinib in chronic myeloid leukemia patients with variant translocations. Methods: Forty eight chronic myeloid leukemia patients carrying variant translocations...
Development of a recurrent pleural effusion in a patient with pulmonary arterial hypertension treated with imatinib
Pulmonary Hypertension Imatinib Tyrosine Kinase Inhibitors Pleural Effusion
2013/1/29
Pulmonary arterial hypertension (PAH) is a devastating disease associated with progressive elevation in pulmonary pressures that eventually leads to chronic right heart failure and death. At present, ...
Kinetics of BCR-ABL Transcripts in Imatinib Mesylate treated Chronic Phase CML (CPCML), A Predictor of Response and Progression Free Survival
CML imatinib mesylate molecular responses cytogenetic responses ABL kinase mutations
2009/10/26
Purpose: To assess the kinetics of molecular response to Imatinib Mesylate (IM) therapy in predicting progression free survival (PFS), sustained hematological, and cytogenetic responses in CPCML. Meth...