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Effects of potassium supplements on glucose metabolism in African Americans with prediabetes: a pilot trial
potassium chloride potassium risk factor glucose metabolism prediabetes African Americans
2018/11/21
Background: Low potassium has been identified both as a risk factor for type 2 diabetes and as a mediator of the racial disparity in diabetes risk. Low potassium could be a potentially modifiable risk...
A systematic review and meta-analysis of nutrition therapy compared with dietary advice in patients with type 2 diabetes
dietary advice individualized nutrition therapy meta-analysis review type 2 diabetes
2018/11/21
Background: Despite recommendations, many patients with type 2 diabetes receive dietary advice from nurses or doctors instead of individualized nutrition therapy (INT) that is provided by a dietitian.
熊果酸对急性心肌梗死小鼠氧化应激和脂质代谢的影响
急性心肌梗死 熊果酸 氧化应激 脂质代谢
2018/9/19
观察熊果酸对急性心肌梗死小鼠心肌的保护作用机制。 方法 30只C57小鼠随机均分为假手术组、急性心肌梗死模型组和熊果酸组。熊果酸组和急性心肌梗死模型组结扎冠状动脉左前降支6 h,收集各组小鼠心脏和血清。硝基四氮唑(NBT)染色检测心肌梗死面积,HE染色检测心肌病理形态,全自动生化分析仪检测血清乳酸脱氢酶(LDH)、磷酸肌酸激酶(CPK)、心肌肌钙蛋白I(cTnI)、甘油三酯(TG)、总胆固醇(TC...
No metabolic effects of mustard allyl-isothiocyanate compared with placebo in men
mustard allyl-isothiocyanate energy expenditure thermogenesis thermogenic food
2018/11/20
Background: Induction of nonshivering thermogenesis can be used to influence energy balance to prevent or even treat obesity. The pungent component of mustard, allyl-isothiocyanate (AITC), activates t...
Iron status of toddlers, nonpregnant females, and pregnant females in the United States
ferritin soluble transferrin receptor total-body iron iron deficiency toddlers women of reproductive age hemoglobin
2018/11/22
Background: Total-body iron stores (TBI), which are calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to assess the iron status of populations in the United S...
Serum ferritin as an indicator of iron status: what do we need to know
iron status, iron deficiency, ferritin, iron deficiency anemia, cutoffs, hepcidin, diagnostic test
2018/11/22
Determination of iron status in pregnancy and in young children is essential for both clinical and public health practice. Clinical diagnosis of iron deficiency (ID) through sampling of bone marrow to...
Excess iron: considerations related to development and early growth
brain early growth erythropoiesis excess iron iron metabolism ron toxicity pregnancy stem cells
2018/11/21
What effects might arise from early life exposures to high iron? This review considers the specific effects of high iron on the brain, stem cells, and the process of erythropoiesis and identifies gaps...
Low serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi
arachidonic acid carnitine dehydroepiandrosterone docosahexaenoic acid malnutrition pregnenolone sulfate stunting
2018/11/21
Background: Stunting affects ~25% of children <5 y of age and is associated with impaired cognitive and motor development and increased morbidity and mortality. The pathogenesis of stunting is poorly ...
Salt substitution is a promising but unproven intervention for stroke management
Salt substitution promising stroke management
2018/11/20
In this issue of the Journal, Pan et al. (1) report beneficial effects on recovery after stroke with 6 mo of the postacute use of a salt substitute. The trial switched regular salt (sodium chloride) f...
Placental vitamin D metabolism and its associations with circulating vitamin D metabolites in pregnant women
vitamin D pregnancy placenta trophoblasts vitamin D metabolism 25-hydroxyvitamin D megalin/cubilin CYP2R1 CYP27B1 CYP24A1
2018/11/21
Background: Little is known about placental vitamin D metabolism and its impact on maternal circulating vitamin D concentrations in humans.
Comparison of midupper arm circumference and weight-for-height z score for assessing acute malnutrition in Bangladeshi children aged 6–60 mo: an analytical study
community-based management of acute malnutrition detection of malnutrition in children aged <5 y midupper arm circumference wasting weight-for-height z score
2018/11/20
Background: In clinical settings, wasting in childhood has primarily been assessed with the use of a weight-for-height z score (WHZ), and in community settings, it has been assessed via the midupper a...
Effect of prior meal macronutrient composition on postprandial glycemic responses and glycemic index and glycemic load value determinations
glycemic index and glycemic load glycemic response healthy participants macronutrient composition nonesterified fatty acids
2018/11/20
Background: The potential impact of prior meal composition on the postprandial glycemic response and glycemic index (GI) and glycemic load (GL) value determinations remains unclear.
Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double-blind trial in overweight humans
dietary protein protein source high-protein diet gut microbiota,
2018/11/16
Background: Although high-protein diets (HPDs) are frequently consumed for body-weight control, little is known about the consequences for gut microbiota composition and metabolic activity and for lar...
Randomized controlled trial on the impact of early-life intervention with bifidobacteria on the healthy infant fecal microbiota and metabolome
infant gut microbiota probiotics bifidobacteria breastfeeding 16S rRNA gene metabolomics
2018/11/20
Background: Early-life colonization of the intestinal tract is a dynamic process influenced by numerous factors. The impact of probiotic-supplemented infant formula on the composition and function of ...
Moderate-to-vigorous physical activity, but not sedentary time, predicts changes in cardiometabolic risk factors in 10-y-old children: the Active Smarter Kids Study
physical activity sedentary time cardiometabolic risk factors
2018/11/16
Recently, Skrede et al. (1) prospectively examined the association of objectively measured sedentary time and subcomponents of physical activity with individual and clustered cardiometabolic risk fact...