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An outbreak of unusual respiratory disease, initially dominated by pneumonia, in Wuhan, China, is caused by infection by a novel coronavirus.The new virus was initially named 2019-nCoV by WHO.1–3
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes
2019-nCoV Wuhan pneumonia epidemiology swabs intestine
2020/6/12
In December 2019, a novel coronavirus (2019-nCoV) caused an outbreak in Wuhan, China, and soon spread to other parts of the world. It was believed that 2019-nCoV was transmitted through respiratory tr...
关于湖北省各地区流动人口状况与疫情防控建议（图）
湖北省 各地区 流动人口状况 疫情防控建议
2020/5/18
春节是我国传统中最重要的节日，春节前后也是人口流动最为频繁的时期。春节前流动人口离开常住地回到户籍地，春节后流动人口则从户籍地返回常住地。本文综合使用人口宏观管理与决策信息系统（PADIS）跨省流动人口平台2018年全国跨省流动人口个案数据库【1】、全国流动人口报表数据和动态监测调查数据,对湖北省影响新型冠状病毒肺炎传播的重点地区流动人口进行分析，提出疫情防控建议。
The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus
Coronavirus 2019-nCoV SARS-CoV Pneumonia Acute respiratory syndrome Disease X
2020/6/12
Based on the announcement of the World Health Organization (WHO) in 2018, the Wuhan pneumonia caused by an unknown etiology should be recognized as the first Disease X. Later, the pathogen was identif...
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Fusion mechanism 2019-nCoV inhibitors targeting HR1 domain spike protein
2020/6/12
Very recently, a novel coronavirus, 2019-nCoV, emerged in Wuhan, China and then quickly spread worldwide, resulting in >17,388 confirmed cases and 361 deaths as of 3 February 2020, thus calling for th...
从人口流动看新型肺炎疫情的发展（图）
人口流动 新型肺炎 疫情发展
2020/5/18
近日来，每日的新型肺炎疫情动态变化牵动着无数人的心，除了赶赴重疫区支援的一线工作者外，很多学者从不同的角度对疫情的发展态势及主要风险点也进行了分析。本文使用官方公布的疫情数据，结合流动人口监测调查和百度地图实时数据，从人口迁移流动的视角对各地的疫情传播风险进行了初步的讨论。
Clinical Features and Treatment of 2019-nCov Pneumonia Patients in Wuhan: Report of A Couple Cases
Clinical Features Treatment 2019-nCov Pneumonia Patients Wuhan
2020/6/12
Till January 20, 2020, the 2019-new coronavirus (2019-nCoV) has caused more than one hundred cases in Wuhan (WMHC 2020). During a retrospective study of recent pneumonia patients in our department, we...
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
Remdesivir chloroquine effectively inhibit novel coronavirus (2019-nCoV) vitro
2020/6/12
In December 2019, a novel pneumonia caused by a previously unknown pathogen emerged in Wuhan, a city of 11 million people in central China. The initial cases were linked to exposures in a seafood mark...
A pneumonia outbreak associated with a new coronavirus of probable bat origin
pneumonia outbreak associated new coronavirus probable bat origin
2020/6/12
Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats1,2,3,4...
An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies
emerging coronaviru pneumonia outbreak Wuhan China: calling developing therapeutic prophylactic strategies
2020/6/12
In December of 2019, an outbreak of pneumonia caused by an unknown aetiology occurred in Wuhan, China and most patients were linked to a single seafood market, which reportedly sold seafood and some l...
指环病毒6实时荧光定量PCR检测体系的建立与验证
指环病毒6 实时荧光定量PCR 敏感性 特异性
2020/3/10
建立指环病毒(Torque teno virus，TTV)6实时荧光定量PCR检测体系，并验证检测体系的敏感性与特异性。根据GenBank中登录的TTV6基因序列设计引物与FAM-Eclipse探针，建立基于FAM-Eclipse探针法的实时荧光定量PCR检测方法，建立标准曲线并进行敏感性与特异性分析。
深圳市自然条件下温度趋势对白纹伊蚊繁殖的影响
白纹伊蚊 温度趋势 诱蚊诱卵器指数 产卵率
2020/5/28
研究自然条件下温度对白纹伊蚊繁殖的影响，为预测其种群动态及蚊虫控制提供数据支持。方法 2016-2018年每月在深圳市内选择居民区、医院及公园外环境各至少1处布放诱蚊诱卵器，通过回收的诱蚊诱卵器分析在自然条件下温度趋势对诱蚊诱卵器指数（MOI）及产卵率的影响。采用单样本t检验进行一组样本内的差异性比较。
老挝南部沙湾拿吉省农县居民区成蚊种类构成调查
蚊种构成 诱蚊灯法 优势蚊种 老挝沙湾拿吉省农县
2020/5/28
调查老挝南部沙湾拿吉省农县居民区成蚊种类构成，为制定当地重要蚊媒传染病防控对策与措施提供科学依据。方法 采用诱蚊灯通宵捕蚊法和电动捕蚊器法在居民区采集成蚊，并采用形态学方法鉴定蚊虫种类。
调查威海市文登区发热伴血小板减少综合征病例的基本特征以及发病和死亡的危险因素，为其精准防控提供科学依据。方法 采用现场调查的方法，收集病例的临床和流行病学信息；采集同村健康人、动物和蜱标本，采用实时荧光定量PCR和ELISA方法，检测病毒特异性核酸和抗体，比较不同特征标本的抗体阳性率差异是否有统计学意义。