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HOUSTON – (Dec. 16, 2014) – Rice University scientists have detected at least three instances of cross-species mating that likely influenced the evolutionary paths of “old world” mice, two in recent t...
Sex Difference in Calbindin Cell Number in the Mouse Preoptic Area: Effects of Neonatal Estradiol and Bax Gene Deletion
Sex Difference Calbindin Cell Number Mouse Preoptic Area Neonatal Estradiol Bax Gene Deletion
2014/12/12
The sexually dimorphic nucleus of the preoptic area (SDN-POA) was first discovered in rats and is one of the most famous and best studied sex differences in the field of neuroscience. Though well docu...
Cloning and characterization of a new gene involved in lymphocyte activation
The immune system mouse models cow in vitro lymphocyte activation immunology lymphocyte activated gene
2014/12/11
Cattle represent an economically important species whose immune system seems to depart from the standard human and murine models. Little has been documented about bovine lymphocyte activation in vitro...
{\it CSE1}, an essential yeast gene required for cell cycle progression, encodes a nuclear transport factor
Brewing yeast genes chromosomes genes cell cycle and protein nuclear proteins
2014/12/11
CSE1, an essential Saccharomyces cerevisiae gene was initially isolated in a screen for genes important for accurate chromosome segregation. cse1 mutants have pleiotropic phenotypes including defects ...
Understanding mitochondrial biogenesis through gene relocation
Yeast the genes oxidative phosphorylation enzymes proteins small ribosomes membrane protein the catalyst
2014/12/11
The yeast mitochondrial genome encodes seven hydrophobic subunits of oxidative phosphorylation enzymes and Var1p, an essential protein in the small ribosomal subunit. Expression of the membrane protei...
Maternal thyroid hormone regulates gene expression in the fetal rat brain
Clinical thyroid hormone the fetus gene
2014/12/11
Recent clinical evidence indicates that thyroid hormone plays an essential role in fetal brain development. However, the mechanism by which thyroid hormone affects development has been largely unexplo...
Characterization and analysis of the cuticlin gene family of the human parasite Onchocerca volvulus
Onchocerciasis silk worm parasites river blindness in Africa plate tail volvulus infectious blindness life cycle the human host bone corneous layer
2014/12/11
Onchocerciasis, or African River blindness caused by the filarial parasite Onchocerca volvulus is the second leading cause of infectious blindness world-wide, with over 18 million people infected. The...
Energy availability signals and the prohormone convertase 1 gene are regulated by Nhlh2
Gene regulation signals transcription factors leptin thalamus arcuate nucleus neurons
2014/12/11
Body weight is controlled by gene regulation through the activation of signal transduction pathways which ultimately regulate transcription factors and their gene targets. Fluctuating leptin levels re...
Novel developmental functions of the Drosophila SOX gene Dichaete
Cell biology a fertilized egg embryo cell state factor regulation gene subset of mammalian proteins
2014/12/11
All multicellular life begins as a single cell—the fertilised egg, from which the adult organism develops. As a general priniciple, as embryos progess through development, changes in cellular status s...
Molecular mechanisms through which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) interferes with estrogen regulation of PRL gene expression in vivo and in vitro
Aromatic hydrocarbon environmental pollution chemicals adipose tissue plasma gland hormone
2014/12/11
Polyhalogenated aromatic hydrocarbon (PHAH) belongs to a group of ubiquitous environmental contaminants. Among them, 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) is one of the most toxic synthetic chem...
Identification And Functional Characterization Of Zebrafish Gene Technotrousers (tnt)
Biological sciences Behavior Glial glutamate transporter Locomotion Motor develoment Zebrafish Technotrousers
2014/12/10
Neural networks in the hindbrain and spinal cord require a proper balance between excitation and inhibition. Identification of zebrafish mutants that have defects in motor output mediated by these net...
Identification and Functional Characterization of the Zebrafish Gene Quetschkommode (que)
dbt disease models metabolism MSUD neurodegenerative diseases zebrafish
2014/12/10
Locomotion in vertebrates depends on proper formation and maintenance of neuronal networks in the hind-brain and spinal cord. Malformation or loss of factors required for proper maintenance of these n...
A Novel Approach For Stable, Cell-Type Restricted Knockdown of Gene Expression in C.ELEGANS
Biological sciences Cell-type restricted knockdown Gene expression C. elegans
2014/12/10
Removal of protein activity by genetic mutation or pharmacological inhibition has been used extensively to understand the normal function of a protein. However, null mutations eliminate gene function ...
A Hierarchical Spherical Radial Quadrature Algorithm for Multilevel GLMMS, GSMMS, and Gene Pathway Analysis
Generalized Semiparametric Mixed Model multilevel Spherical Radial splines
2014/12/8
The first part of my thesis is concerned with estimation for longitudinal data using generalized semi-parametric mixed models and multilevel generalized linear mixed models for a binary response. Like...
Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid
L-ascorbic acid cardiometabolic traits confounding genetic variants reverse causation
2018/12/20
Background: Observational studies showed that circulating L-ascorbic acid (vitamin C) is inversely associated with cardiometabolic traits. However, these studies were susceptible to confounding and re...