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Atrial natriuretic peptide precursor material in rat testis
ANP mRNA RF-HPLC northern blot hybridization
2009/2/6
Atrial natriuretic peptide (ANP) has recently been suggested to play a role in the regulation of male reproduction. Specifically, it has been shown to affect steroidogenesis in Leydig cells. The dat...
Changing relationships between testis size, Sertoli cell number and spermatogenesis in Sprague-Dawley rats
reproduction testes gametogenesis correlations
2009/2/6
Relationships between several reproductive characteristics were investigated in 25 Sprague-Dawley rats aged 60, 150, and 240 days (n = 75). Daily sperm production correlated with body weight (r = 0....
Spermatic cord torsion: effects of cyclosporine and prednisone on fertility and the contralateral testis in the rat
spermatic cord torsion immunosuppression testicular damage
2009/2/6
Unilateral spermatic cord torsion results in contralateral degeneration and reduced fertility in the prepubertal male rat. This study was conducted to investigate the use of immunosuppression with c...
Does ethane 1,2-dimethanesulphonate（EDS）have a direct cytotoxic effect on the seminiferous epithelium of the rat testis?
spermatogenesis cytotoxic testosterone testes rat
2009/2/6
The authors examined the possibility that ethane 1,2-dimethanesulphonate (EDS) has a cytotoxic effect on spermatogenesis that is not secondary to androgen withdrawal resulting from the well known cy...
Age as a factor influencing the power and sensitivity of experiments for assessing body weight, testis size, and spermatogenesis in rats
Experimental design daily sperm production spermatogenesis testes
2009/2/6
Data from 25 rats aged 60, 150, or 240 days (n = 75) were used to determine the number of observations per rat and or rats per treatment group needed to provide future experiments of known power and...
Expression and Regulation of Aquaporins 1, 8, and 9 in the Testis, Efferent Ducts, and Epididymis of Adult Rats and During Postnatal Development
channels Sertoli cells Leydig cells principal cells clear cells nonciliated cells
2008/12/30
Aquaporins (AQPs) are membrane protein channels that allow the rapid passage of water through an epithelium containing tight junctions. In the present study, light microscope immunocytochemistry ...
The testis as a major source of circulating inhibins in the male equine fetus during the second half of gestation
Horse fetal tests inhibin A inhibin pro-C Sertoli
2008/12/30
Immunolocalization of the inhibin (a) and inhibin/activin (beta3A and betaB) subunit proteins in equine fetal testes was investigated to determine the ability of the fetal testis to produce inhibi...
Expression, action, and regulation of transforming growth factor alpha and epidermal growth factor receptor during embryonic and perinatal rat testis development
FSH gametogenesis mesenchymal-epithelial Sertoli
2008/12/29
The objective of the current study was to extend previous observations and examine the expression pattern and effects of transforming growth factor alpha (TGFalpha) and epidermal growth factor recep...
Impairment of spermatogenesis in transgenic mice with selective overexpression of Bcl-2 in the somatic cells of the testis
Apoptosis Bax Sertoli cell Leydig cell endocrine dysfunction
2008/12/29
To explore the functional role of Bcl-2 in germ cell development, transgenic mice carrying 6 kilobases of the inhibin-alpha promoter were generated to express human bcl-2 gene product in the gona...
Testicular pathology in 46,XY dysgenetic male pseudohermaphroditism：an approach to pathogenesis of testis cancer
Gonadal dysgenesis gonadotropins testicular carcinoma in situ
2008/12/29
Eleven children with dysgenic male pseudohermaphroditism (DMP) and 18 boys with isolated penile hypospadias, all with 46,XY karyotype, were studied. Testicular dysgenesis was associated with signifi...
Immortalized testis cell lines from estrogen receptor（ER）alpha knock-out and wild-type mice expressing functional ERalpha or ERbeta
Immortalization HPV E6/E7 in vitro models
2008/12/29
The surprising findings that male mice lacking the estrogen receptor (ER) alpha (alphaERKO) have atrophic testis and are infertile proved that ERalpha is involved in normal testicular function. To o...
Assessment of the androgen environment within the human testis：minimally invasive method to obtain intratesticular fluid
Testosterone spermatogenesis ABP
2008/12/29
Previous studies of the rat have shown that testosterone concentrations within the interstitial and seminiferous tubularfluids of the testes are significantly higher than normal serum levels, and furt...
Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat
diethylstilbestrol blood-testis rat
2008/12/26
Newborn rats were treated with 10 microg of diethylstilbestrol (DES) on alternate days from the 2nd to the 12th postnatal day, and the testes were sequentially examined up to 105 days of age by light,...
Thyroid hormone receptors in neonatal, prepubertal, and adult rat testis
Thyroid hormone receptors adult rat testis
2008/12/26
Thyroid hormone (TH) is involved in the differentiation and development of rat testis, whereas its role in adult testis function is still undefined. The aim of our work has been to further analyze the...
The effect of cardiac arrest on the blood-testis barrier to albumin, tumor necrosis factor-alpha, pituitary adenylate cyclase activating polypeptide, sucrose, and verapamil in the mouse
blood-testis albumin tumor necrosis factor-alpha pituitary adenylate cyclase
2008/12/26
Impotence commonly occurs after events such as acute myocardial infarction, coronary bypass, head trauma, and cerebral bleeding, including subarachnoid hemorrhage. We hypothesize that the hypoxia ac...