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Incidence and risk factors of post-transplant diabetes mellitus among transplanted renal allograft recipients
Transplant Diabetes mellitus Oral glucose tolerance test Kidney
2015/9/11
Background: Post-transplant diabetes mellitus (PTDM) contributes to the risk for cardiovascular diseases and infection, reducing graft and patient survival. This study was conducted to identify the in...
家族高发性2型糖尿病的遗传模式研究Studies on Genetic Model in Familial Type 2 Diabetes Mellitus
2型糖尿病 遗传模式 复合分离分析 遗传率
2008/1/16
对1999～2000年门诊及住院的家族高发性2型糖尿病患者为先证者的136个大家系进行研究，以探讨该病的遗传模式。对家系人群采用Falconer 法估算遗传率，用Penrose法进行多基因分析，并用S.A.G.E-REGD软件拟合A型回归Logistic模型进行复合分离分析的方法，对家族高发性2型糖尿病家系进行研究。结果表明，136个大家系的2型糖尿病遗传率为94.07%±5.84%，提示在这些家...
磺酰脲类受体基因多态性与2型糖尿病的相关性研究Study on the Relationship between Sulfonylurea Receptor 1 Gene Polymorphism and Type 2 Diabetes Mellitus
2型糖尿病 磺酰脲类受体1 基因多态性
2008/1/10
摘要 研
究磺酰脲类受体1（SUR1）基因外显子16-3c/t多态性在中国某南方汉族人群中是否为2型糖尿病的致病基因座。采用聚合酶链反应-限制酶酶切片段长度多态性（PCR-RFLP）方法对南方汉族46个2型糖尿病高发家系成员的SUR1基因外显子16的多态性进行分析。利用Mantel-Haenszel分层分析研究该基因座多态性与2型糖尿病的关系。在高发家系人群中，SUR1基因外显子16-3c/t多...
解偶联蛋白与肥胖及2型糖尿病发病的关系Role of Uncoupling Proteins in the Pathogenesis of Obesity and Type II Diabetes
解偶联蛋白 肥胖 2型糖尿病 能量代谢 基因多态
2007/12/30
摘要解偶联蛋白（UCPs）是线粒体内膜上的一种转运蛋白，它能够降低线粒体内膜上的质子梯度，使底物氧化和ADP磷酸化解偶联，减少ATP的产生。基于其功能，解偶联蛋白基因被视为肥胖病及2型糖尿病的重要候选基因。UCP同系物过表达的遗传工程小鼠表现出对饮食导致的肥胖具有耐受性，同时UCP2基因3＇非翻译区的45bp插入／缺失以及UCP3基因C-55T多态与肥胖表型的相关性等研究结论支持这一假说。本文对U...
期刊信息
篇名
Adipocyte lipid diabetes Diabetes, Lipids and Adipocyte Secretagogues
语种
英文
撰写或编译
撰写
作者
May Faraj,LU Hui-ling,Cianflone K
第一作者单位
May Faraj,Cianflone K.Laboratory for Cardiovascular Research, R...
Roles of adipocyte derived hormone adiponectin and resistin in insulin resistance of type 2 Diabetes
2007/7/28
期刊信息
篇名
Roles of adipocyte derived hormone adiponectin and resistin in insulin resistance of type 2 Diabetes
语种
英文
撰写或编译
撰写
作者
Hui-Ling LU,Hong-Wei Wang,Yu Wen,Mu-Xun Zhang,Han-Hua Lin
第一作者单位
Hui-Ling...
4 December 2006，Speaking at the 19th World Diabetes Congress in Cape Town, South Africa, Giancarlo Viberti, Professor of Diabetes and Metabolic Medicine at King's, outlined the findings of the ADOPT s...
COMPARISON OF MATERNAL AND FETAL/NEONATAL COMPLICATIONS IN GESTATIONAL AND PRE-GESTATIONAL DIABETES MELLITUS
Pre-gestational diabetes mellitus gestational diabetes mellitus maternal complications
2010/2/5
Presence of maternal diabetes mellitus (DM) during pregnancy has important consequences for both mother and child. To determine maternal and fetal/neonatal complications of gestational DM and compare ...
Evaluating the Format and Effectiveness of a Disease State Management Training Program for Diabetes
Disease State Management Training Program Diabetes
2016/3/15
The objective of this project was to determine whether a continuing educational approach to disease state management training in diabetes mellitus is an effective means of improving both cognitive kno...