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Effects of Respiratory Syncytial Virus Infection on Dendritic Cells and Cysteinyl Leukotrienes in Lung Tissues of a Murine Model of Asthma
asthma cysteinyl leukotrienes dendritic cell Dermatophagoides farinae respiratory syncytial virus
2010/11/18
Background: Pulmonary dendritic cells (DCs) play critical roles in both allergy and in viral infection. Levels of cysteinyl leukotrienes (cysLTs) increase after allergen sensitization and viral infect...
The pharmacotherapy of asthma is a complex and evolving topic. A detailed understanding of the pathophysiologic processes involved in the asthmatic response forms the basis for understanding the actio...
The Relationship between Exhaled Nitric Oxide Measured with an Off-line Method and Airway Reversible Obstruction in Japanese Adults with Asthma
airflow reversible obstruction asthma exhaled nitric oxide off-line method
2010/11/18
In patients with obstructive impairment, eNO reflects the degree of reversible airflow limitation. In subjects with normal pulmonary function, eNO may facilitate the diagnosis and management of asthma...
The Distinctive Effects of Acute and Chronic Psychological Stress on Airway Inflammation in a Murine Model of Allergic Asthma
airway inflammation bronchial asthma opioid psychological stress μ-opioid receptor
2010/11/18
In BALB/c mice, but not in C57BL/6 mice, the number of total cells, eosinophils and lymphocytes in the acute stress group were significantly decreased compared with those in the non-acute stress group...
Invariant Natural Killer T (iNKT) Cells in Asthma: A Novel Insight into the Pathogenesis of Asthma and the Therapeutic Implication of Glycolipid Ligands for Allergic Diseases
allergic asthma glycolipid ligand invariant NKT cells Th2 cytokine T helper (Th) 2 cell α-galactosylceramide
2010/11/18
Allergic bronchial asthma is a complex inflammatory diseases originated from dysregulated immune responses in the respiratory mucosa. The inflammatory state in asthmatic lung is characterized by massi...
The E-selectin mediates the interaction of activated endothelial cells with leukocytes and plays a
fundamental role in the pathogenesis of asthma. It has been suggested that an S/R (Serine128Arginine...
Multiple Urban and Asthma-Related Risks and Their Association with Asthma Morbidity in Children
asthma risks urban
2009/12/21
Objective To determine whether a multi-dimensional cumulative risk index (CRI) is a stronger predictor of asthma morbidity in urban, school-aged children with asthma, than poverty or severity alone. ...
A Prospective Survey on Safety of Sustained-Release Theophylline in Treatment of Asthma and COPD
adverse drug reactions asthma COPD safety evaluation sustained-release theophylline
2010/11/19
3,921 patients were included in the safety evaluation. No serious adverse reactions were observed among the patients in this survey, although 54 patients (1.38%) exhibited non-serious adverse reaction...
Respiratory Viral Infections and Early Asthma in Childhood
allergy asthma childhood respiratory viral infection
2010/11/19
Respiratory viral infections profoundly influence the disease activity of wheezing illnesses and asthma in early childhood. Viral bronchiolitis shares many features with asthma and a subset of childre...
Microarray-based Identification of Novel Biomarkers in Asthma
asthma inflammation interleukin-13 mast cells microarray
2010/11/19
Bronchial asthma is a complicated and diverse disorder affected by genetic and environmental factors. It is widely accepted that it is a Th2-type inflammation originating in lung and caused by inhalat...
Association of the Expression of IL-4 and IL-13 Genes,IL-4 and IgE Serum Levels with Allergic Asthma
Asthma Genes IL-4 IL-13 RT-PCR
2010/4/9
Immune and inflammatory responses mediated by cytokines, play important roles in the
pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines
such as IL-4 and I...
Association of the Expression of IL-4 and IL-13 Genes,IL-4 and IgE Serum Levels with Allergic Asthma
Asthma Genes IL-4 IL-13 RT-PCR
2010/4/9
Immune and inflammatory responses mediated by cytokines, play important roles in the
pathophysiology of asthma. These responses are associated with overexpression of Th2 cytokines
such as IL-4 and I...
Comparative Efficacy of Dexamethasone versus Hydrocortisone in Severe Acute Pediatric Asthma
Asthma dexamethasone Hydrocortisone
2010/4/19
This study aimed to compare the efficacy of dexamethasone and hydrocortisone in the treatment of acute paediatric asthma. Forty seven asthmatic children were randomised to receive either dexamethasone...