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Biosensor Arrays and Methods
Biosensor Arrays Methods
2016/5/24
A surface detector array device suitable for use with a biosensor is disclosed. The device is formed of a substrate having a surface defining a plurality of distinct bilayer-compatible surface regions...
Arrays of Mobile Tethered Vesicles on Supported Lipid Bilayers
Oligonucleotides,Antisense Lipid Bilayers Phosphatidylcholines Fluorescent Dyes Liposomes
2016/5/24
We report a new system of laterally mobile, arrayed vesicles that are encoded with DNA to control tethering to fluid-supported phospholipid bilayers. The motion of individual fluorescently labeled ves...
Arrays of Independently-Addressable Supported Fluid Bilayer Membranes
Arrays Independently Addressable Fluid Bilayer Membranes
2016/5/23
A surface detector array device suitable for use with a biosensor is disclosed. The device is formed of a substrate having a surface defining a plurality of distinct bilayer-compatible surface regions...
Patterning and Composition Arrays of Supported Lipid Bilayers by Microcontact Printing
biological molecules-nucleic acids self-assembly scanning tunneling microscopy gold
2016/5/23
Fluid-supported lipid bilayers self-assemble on glass and SiO2 surfaces. We have found that it is also possible to assemble fluid bilayers on plasma-oxidized polydimethyl siloxane (PDMS) surfaces. Fur...
Formation of Supported Lipid Bilayer Composition Arrays by Controlled Mixing and Surface Capture
tetrafluorophosphite mean amplitudes of vibration bond properties
2016/5/23
Virtually all structures in living cells are defined by lipid bilayers. Many molecular components can diffuse along these 2-dimensional structures, sampling all or part of the membrane, and this diffu...
Brownian Ratchets: Molecular Separations in Lipid Bilayers Supported on Patterned Arrays
4-Chloro-7-nitrobenzofurazan Chemistry, Physical Diffusion Electrophoresis Fluorescence Fluorescent Dyes Lipid Bilayers Membrane Fluidity Membrane Proteins Membrane Proteins Phosphatidylethanolamines Phosphatidylethanolamines Phosphatidylserines Phosphatidylserines Phospholipids Phospholipids Physicochemical Phenomena Temperature Xanthenes
2016/5/23
Brownian ratchets use a time-varying asymmetric potential that can be applied to separate diffusing particles or molecules. A new type of Brownian ratchet, a geometrical Brownian ratchet, has been rea...
Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays
Site Tiling Analysis accurate discovery
2015/12/11
High-throughput genotype data can be used to identify genes important for local adaptation in wild populations,
phenotypes in lab stocks, or disease-related traits in human medicine. Here we advance...
Development and Application of High-density SNP Arrays in Genomic Studies of Domestic Animals
Whole-genome Sequencing HapMap SNP Array Genomics Domestic Animals
2016/5/5
In the past decade, there have been many advances in whole-genome sequencing in domestic animals, as well as the development of “next-generation” sequencing technologies and high-throughput genotyping...