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DHA-rich n–3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
fish oil DHA EPA DNA methylation LINE-1 Alzheimer disease
2018/11/20
Background: Dietary fish oils, rich in long-chain n–3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n–3) and eicosapentaenoic acid (EPA, 20:5n–3)], modulate inflammatory reactions thro...
Dietary fatty acid intake after myocardial infarction: a theoretical substitution analysis of the Alpha Omega Cohort
dietary fatty acids cardiac patients cardiovascular disease
2018/11/19
Background: Replacement of saturated fatty acids (SFAs) with unsaturated fatty acids (UFAs), especially polyunsaturated fatty acids (PUFAs), has been associated with a lower risk of ischemic heart dis...
Dietary fatty acid intake after myocardial infarction: a theoretical substitution analysis of the Alpha Omega Cohort
dietary fatty acids cardiac patients cardiovascular disease coronary heart disease substitution analysis prospective cohort study
2018/11/16
Background: Replacement of saturated fatty acids (SFAs) with unsaturated fatty acids (UFAs), especially polyunsaturated fatty acids (PUFAs), has been associated with a lower risk of ischemic heart dis...
Effect of maternal high dosages of folic acid supplements on neurocognitive development in children at 4–5 y of age: the prospective birth cohort Infancia y Medio Ambiente (INMA) study
folic acid supplements folate pregnancy periconception period child neurocognitive development
2018/11/19
Background: The benefits of the use of folic acid supplements (FASs) during the periconception period to prevent neural tube defects and to ensure normal brain development in offspring are well known....
Folic acid: the solution for treating asymptomatic hyperuricemia?
Folic acid solution asymptomatic hyperuricemia
2018/11/13
Among patients with gout, the increased risk of hypertension and cardiovascular diseases has often been attributed to hyperuricemia (1). Further research confirmed that asymptomatic hyperuricemia, whi...
Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT)
controlled hyperuricemia olic acid supplementation new-onset hyperuricemia total homocysteine uric acid concentrations
2018/11/13
Background: The effect of folic acid supplementation on uric acid (UA) concentrations is still inconclusive.
Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention
Chinese folic acid hyperglycemia hypertension stroke
2018/11/13
Background: Diabetes is a known risk factor for stroke, but data on its prospective association with first stroke are limited. Folic acid supplementation has been shown to protect against first stroke...
A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study
DHA EPA inflammation men and women randomized controlled trial risk factors
2018/12/13
Background: To date, most studies on the anti-inflammatory effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in humans have used a mixture of the 2 fatty acids in various forms and...
Glyphosate and aminomethylphosphonic acid are not detectable in human milk
AMPA glyphosate human milk lactation organic food aminomethylphosphonic acid, breastfeeding environmental contaminants pesticide
2018/11/30
Background: Although animal studies have shown that exposure to glyphosate (a commonly used herbicide) does not result in glyphosate bioaccumulation in tissues, to our knowledge there are no published...
Effects of Short-Term Docosahexaenoic Acid Supplementation on Markers of Inflammation after Eccentric Strength Exercise in Women
Delayed-onset muscle soreness omega-3 fatty acids fish oil
2016/3/11
The omega-3 fatty acid docosahexaenoic acid (DHA) has anti-inflammatory and anti-nociceptive (pain inhibiting) effects. Because strenuous exercise often results in local inflammation and pain, we hypo...
In a single-blind, matched group design: branched-chain amino acid supplementation and resistance training maintains lean body mass during a caloric restricted diet
Cut diet Fat mass Lean mass
2016/3/1
Athletes and active adults many times have the goal of improving/maintaining fitness while losing
weight and this is best achieved by caloric restriction in combination with exercise. However, this p...
Maternal single nucleotide polymorphisms in the fatty acid desaturase 1 and 2 coding regions modify the impact of prenatal supplementation with DHA on birth weight
birth weight DHA FADS long-chain PUFAs prenatal supplementation
2018/11/29
Background: Specific single nucleotide polymorphisms (SNPs) in the fatty acid desaturase (FADS) gene affect the activity and efficiency of enzymes that are responsible for the conversion of polyunsatu...
Comparison of the Effects of Eicosapentaenoic Acid With Docosahexaenoic Acid on the Level of Serum Lipoproteins in Helicobacter pylori:A Randomized Clinical Trial
Helicobacter pylori Eicosapentaenoic Acid Docosahexaenoic Acid Cholesterol Triglyceride
2015/10/16
Background: Helicobacter pylori infection is the most common chronic bacterial infection around the world and an important cause of gastrointestinal disorders, which might be involved in the pathogene...
A review on effects of conjugated linoleic fatty acid (CLA) upon body composition and energetic metabolism
conjugated linoleic fatty acid (CLA) body composition energetic metabolism
2015/9/24
Conjugated linoleic acid (CLA) is highly found in fats from ruminants and it appears to favorably modify the body composition and cardiometabolic risk factors. The capacity of CLA to reduce the body f...
Effects of Dietary Acid Load on Exercise Metabolism and Anaerobic Exercise Performance
Renal acid load alkaline diet substrate oxidation respiratory exchange ratio
2015/8/28
Dietary acid load, quantified as the potential renal acid load
(PRAL) of the diet, affects systemic pH and acid-base regulation. In a previous cross-sectional study, we reported that a low
dietary...