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Efficient Algorithms for Multivariate Linear Mixed Models in Genome-wide Association Studies
Efficient Algorithms Multivariate Linear Mixed Models Genome-wide Association Studies
2013/6/17
Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, existing...
Improving power in genome-wide association studies：weights tip the scale
Bonferroni correction Genome-wide association analysis Multiple testing Weightedp-values
2010/4/26
Genome-wide association analysis has generated much discussion about how to preserve power
1 to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multi...