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Proton transfer plays an important role in the optical properties of green fluorescent protein (GFP). While much is known about excited-state proton transfer reactions (ESPT) in GFP occurring on ultra...
Hydrogen bond networks are key elements of protein structure and function but have been challenging to study within the complex protein environment. We have carried out in-depth interrogations of the ...
Synaptic transmission is achieved by exocytosis of small, synaptic vesicles containing neurotransmitters across the plasma membrane. Here, we use a DNA-tethered freestanding bilayer as a target archit...
The charge redistribution upon photoexcitation is investigated for a series of pyrene photoacids to better understand the driving force behind excited-state proton-transfer processes. The changes in e...
We present studies on a series of photosynthetic reaction center (RC) mutants created in the background of the Rhodobacter capsulatus D(LL) mutant, in which the D helix of the M subunit has been subst...
In parts 1 and 2 of this series [Hanson, G. T., McAnaney, T. B., Park, E. S., Rendell, M. E. P., Yarbrough, D. K., Chu, S. Y., Xi, L. X., Boxer, S. G., Montrose, M. H., and Remington, S. J. (2002) Bio...
In bacterial photosynthetic reaction centers, ultrafast singlet excited state energy transfer occurs from the monomeric bacteriochlorophylls, B, and bacteriopheophytins, H, to the homodimer special pa...
The kinetics of triplet energy transfer from the primary electron donor P, a bacteriochlorophyll dimer, to the carotenoid were measured in the M182HL mutant of Rhodobacter sphaeroides photosynthetic r...
The green fluorescent protein (GFP) of the jellyfish Aequorea Victoria has attracted widespread interest since the discovery that its chromophore is generated by the autocatalytic, posttranslational c...
Ultrafast excited state energy transfer to the primary electron donor or special pair in photosynthetic reaction centers has been measured following excitation of the lowest electronic state of the ot...
A 51 bp section of the Rhodobacter capsulatus photosynthetic reaction center M subunit gene (nucleotides M562-M612 of the pufM structural sequence) encoding amino acids M187-M203 was replaced by the h...
The dependence of the rate constant for electron transfer on energy can be systematically studied by measuring kinetics in an applied electric field. General relationships are developed between observ...
Mechanisms of Long Distance Electron Transfer in Proteins:Lessons from Photosynthetic Reaction Centers.
The three-dimensional structure of a photosynthetic reaction center has recently been obtained at atomic resolution using x-ray crystallography by Deisenhofer, Epp, Miki, Huber, and Michel (J. Mol. Bi...
Three chlorophyllide-substitutedhuman hemoglobin (Hb) complexes have been prepared: the tetrameric complex in which zinc pyrochlorophyllide a (ZnPChla) is substituted for all four hemes and the two co...

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