搜索结果: 76-90 共查到“知识库 药物化学”相关记录6215条 . 查询时间(4.082 秒)
目的 考察苦茶妇科凝胶的制备工艺，制备出在阴道环境中能够快速发生相变的温度敏感型原位凝胶。方法 泊洛沙姆P188、P407为凝胶基质，乳酸、乳酸钠为酸缓冲溶液，采用星点设计法筛选原位凝胶的处方工艺，并测定其胶凝温度、胶凝时间、不同酸缓冲溶液对胶凝温度的影响、凝胶稳定性及相关流变学性质。结果 在一定用量范围内，泊洛沙姆P188用量增大胶凝温度逐渐升高，泊洛沙姆P407用量增大胶凝温度逐渐下降，通过星...
A Course Introducing the Principles of Pharmaceutical Care
pharmaceutical care curriculum assessment learner evaluation
2018/5/23
Objectives. To develop, implement, and assess a course that introduces students to the process and application of pharmaceutical care.
Design. The course was offered to students in the third semester...
脂联素与认知障碍的研究进展
脂联素 脂联素受体 认知障碍 发病机制
2020/2/10
脂肪细胞因子是一类由脂肪细胞分泌、具有广泛的生物活性的多肽或蛋白质。脂联素是一种具有胰岛素增敏作用的脂肪细胞因子，具有抗糖尿病、抗动脉粥样硬化和抗炎等作用。脂联素可参与并调控着认知障碍的发生、发展，被认为是一个新的认知障碍的调节因子。
Antihyperlipidemic Statins: A Self-Contained, Clinically Relevant Medicinal Chemistry Lesson
medicinal chemistry dyslipidemia hyperlipidemia statins
2018/4/9
Medicinal chemistry instruction at Creighton University is designed to provide an in-depth, scientifically grounded and clinically relevant learning experience for pharmacy students. Each topic covere...
使用化学键键合的方式分别将叶酸(FA)和5-氟尿嘧啶-1-基乙酸(FUA)偶联于树状大分子聚酰胺-胺(PAMAM)制备纳米载药体系FA-PAMAM-FUA,并结合单因素分析法筛选出最佳制备条件为 FA∶PAMAM∶FUA 的物质的量的比为10∶1∶450,pH值为6.用紫外可见光谱、红外光谱和纳米粒度仪对FA-PAMAM-FUA的光学特性、粒径大小和体外释药性能进行了表征.结果表明:优化条件下制备...
The Enhanced Recovery After Surgery (ERAS) program: benefit and concerns
Enhanced Surgery (ERAS) program benefit concerns
2018/11/14
Enhanced Recovery After Surgery (ERAS) programs have successfully challenged many dogmas that existed in surgery 40 y ago. At that time, as young surgeons, we were taught to slowly increase the oral i...
珠子参药材中皂苷类成分的薄层色谱及HPLC特征图谱研究
珠子参 皂苷成分 薄层色谱 HPLC特征图谱
2017/11/29
建立和完善珠子参药材的薄层色谱及HPLC特征图谱鉴别方法。方法：采用薄层色谱法鉴别珠子参药材中皂苷类成分；采用HPLC法对同一产地不同地块的10批次珠子参药材皂苷类成分进行指纹图谱分析，选用Waters XTerra MS C18色谱柱（250 mm×4.6 mm，5 μm）；流动相为乙腈-0.2%磷酸水溶液，梯度洗脱，分析时间为55 min，检测波长为203 nm。结果：珠子参药材的薄层色谱中皂...
鹿茸的周期性再生是一个基于干细胞的过程，鹿茸干细胞（ASC）存在于生茸区骨膜（AP）与角柄骨膜（PP）中。本篇综述首先提出了一个假说，即紧密包裹的皮肤是ASC微环境的主要组成成分，之后通过一系列实验研究对这一假说进行了验证。通过插膜实验证明ASC和其紧密包裹皮肤之间的相互作用是鹿茸发生与再生不可或缺的，这一相互作用是通过交换游离小分子物质而实现的。AP组织的皮内移植实验表明，表皮和真皮毛乳头细胞参...
An Evidence-Based Review on Medicinal Plants Used as Insecticide and Insect Repellent in Traditional Iranian Medicine
Medicinal Plants Insecticide Insect Repellent Traditional Medicine
2016/1/26
Context: Insects can be the cause of major ecological problems; they can transmit microbes and parasites that affect humans, and damage food crops, trees, and homes. The total economic cost of insect-...
Resistant Strains of Enterotoxigenic Staphylococcus aureus;Unknown Risk for Multiple Sclerosis Exacerbation
Multiple Sclerosis Antibiotic Resistance Iran Enterotoxins Staphylococcus aureus
2015/11/9
Background: Despite all advances in neurological sciences, there are unknown aspects in the epidemiology of multiple sclerosis (MS). Based on this hypothesis, the enterotoxigenic strains of Staphyloco...
耐热炸药的现状及研究进展
有机合成 耐热炸药 制备工艺 起爆感度
2016/7/25
从热性能方面提出了耐热炸药的特点及该类炸药研究的重点；叙述了目前主要耐热炸药PYX、HNS、TATB的性能、制备工艺、应用以及每种耐热炸药的优缺点，说明了应以提高能量和感度为耐热炸药研究的方向；叙述了近年来耐热炸药的主要研究进展，提出了值得重点关注的单质耐热炸药，如LLM-105、NONA、ANPyO等，并对性能、制备工艺、优缺点以及可能应用的领域进行了分析；从耐热性及起爆感度方面对今后的发展提出...
Integrating a New Medicinal Chemistry and Pharmacology Course Sequence into the PharmD Curriculum
medicinal chemistry pharmacology integration alignment curriculum
2018/7/24
Objective. To evaluate the implementation of an integrated medicinal chemistry/pharmacology course sequence and its alignment with a therapeutics series.
Design. Each topic was divided into modules c...
Prevention of endotoxin-induced uveitis in rabbits by Triphala, an Ayurvedic formulation
Triphala Uveitis Endotoxin TNF-α
2015/7/21
Purpose: Triphala (TA) is an Ayurvedic formulation used to treat various disorders. The present study was designed to investigate the anti-inflammatory effect of TA aqueous extract on experimental uve...
Sphingosomes a novel approach to vesicular drug delivery
sphingosomes drug delivery sphingomyelin vesicular system
2015/7/21
Vesicular systems have been realized as extremely useful carrier systems in various scientific domains. Sphingosomes is bilayered vesicles in which an aqueous volume is entirely enclosed by membrane l...