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This dissertation presents a body of research that attempts to tackle the ‘overfitting’ problem for gene signature and biomarker development in two different aspects (mechanistically and computational...
Early gastric carcinomas may develop with a molecular profile differing from sporadic carcinomas occurring at a later age. In this study, we analyzed a retrospective series of 88 patients with gastric...
Throughout history, humanity has referred to reactions occurring with food, plants and, recently, medicines or drugs. The increase in pulmonary tuberculosis cases and the availability of treatment sho...
This study was performed to characterize 35 L. monocytogenes isolates from animals, foods, environmental samples collected between 1997 and 2007 with no apparent epidemiological relations, and five re...
The focus of present study was to determine the epidemiological and molecular aspects of different strains of cystic echinococcosis in Fars province, Iran. Liver and lung samples from 410 sheep, 206 g...
Rottweilers are predisposed to eosinophilic diseases, including hypereosinophilic syndrome. The immunopathogenesis of idiopathic eosinophilia is poorly characterised in dogs and man. Studies in people...
Cathepsin D (CD), a lysosomal protease, and S100A4 protein, a calcium binding motif, are considered to be involved in metastasis in various human cancers. No data regarding such proteins are available...
Meghalaya, one of the Northeast Indian states, is inhabited by two major tribal clusters, Khasi and Garo. The disputed origin of the Lyngngam tribe of Meghalaya is a result of their geographic distrib...
Both WHO and the CDC of Taiwan have reports indicating a dramatic increase in incidence of both syphilis and HIV. With their co-infection, neurosyphilis will become a major issue, and meningovascular ...
Understanding the interaction between nanoparticles (NPs) and cell membranes (dipalmitoylphosphatidylcholine or DPPC bilayers) is important for the design of drug delivery systems and provides insight...
The cytoplasmic level of a messenger RNA, and hence protein, depends not only upon its rates of synthesis,processing, and transport, but its decay rate as well. mRNA decay rates are frequently not sta...
Information technology research has played a significant role in the genomics revolution over the past decade, from aiding with large-scale sequence assembly to automating gene identification to ef...
Cellular behavior is complex. Successfully understanding systems at ever-increasing complexity isfundamental to advances in modern science and unraveling the functional details of cellular behavior ...
Functional medical imaging promises powerful tools for the visualization and elucidation of important disease-causing biological processes in living tissue. Recent research aims to dissect the distrib...
We have synthesized and characterized gold nanoparticles (spheres and rods) with optical extinction bands within the “optical imaging window.” The intense plasmon resonant driven absorption and scatte...

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