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Increased Pain Intensity Is Associated with Greater Verbal Communication Difficulty and Increased Production of Speech and Co-Speech Gestures
Increased Pain Intensity Greater Verbal Communication Difficulty Speech Co-Speech Gestures
2015/5/6
Effective pain communication is essential if adequate treatment and support are to be provided. Pain communication is often multimodal, with sufferers utilising speech, nonverbal behaviours (such as f...
Shining a light on CNTNAP2: complex functions to complex disorders
CNTNAP2 neurogenetics language disorder
2015/5/6
The genetic basis of complex neurological disorders involving language are poorly understood, partly due to the multiple additive genetic risk factors that are thought to be responsible. Furthermore, ...
Hypnotizability and Catechol-O-Methyltransferase (COMT) polymorphysms in Italians
hypnotizability attention COMT absorption selective genotyping haplotype analysis
2015/5/6
Higher brain dopamine content depending on lower activity of Catechol-OMethyltransferase (COMT) in subjects with high hypnotizability scores (highs) has been considered responsible for their attention...
Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment
ALSPAC GWAS imprinting neurodevelopmental disorder specific language impairment
2015/5/5
Specific language impairment (SLI) is a neurodevelopmental disorder that affects linguistic abilities when development is otherwise normal. We report the results of a genome-wide association study of ...
Associations of HLA alleles with specific language impairment
Specific language impairment (SLI) HLA Neurodevelopmental disorders Genetic association
2015/5/5
Human leukocyte antigen (HLA) loci have been implicated in several neurodevelopmental disorders in which language is affected. However, to date, no studies have investigated the possible involvement o...
H3M2:detection of runs of homozygosity from whole-exome sequencing data
H3M2 runs of homozygosity whole-exome sequencing data
2015/5/5
Motivation: Runs of homozygosity (ROH) are sizable chromosomal stretches of homozygous genotypes, ranging in length from tens of kilobases to megabases. ROHs can be relevant for population and medical...
Odors are expressible in language, as long as you speak the right language
Olfaction Color Olfactory naming Cross-cultural Jahai Aslian
2015/5/5
From Plato to Pinker there has been the common belief that the experience of a smell is impossible to put into words. Decades of studies have confirmed this observation. But the studies to date have f...
Termination of ongoing spike-wave discharges investigated by cortico–thalamic network analyses
spike-wave discharges cortico–thalamic network analyses
2015/5/5
Purpose: While decades of research were devoted to study generation mechanisms of spontaneous spike and wave discharges (SWD), little attention has been paid to network mechanisms associated with the ...
EFFECTS OF TRANSPORT ON FECAL GLUCOCORTICOID LEVELS IN CAPTIVE-BRED COTTON-TOP TAMARINS (SANGUINUS OEDIPUS)
FECAL GLUCOCORTICOID LEVELS CAPTIVE-BRED COTTON-TOP TAMARINS
2015/5/5
The relocation of animals can induce stress when animals are placed in novel environmental conditions.The movement of captive animals among facilities is common, especially for non-human primates used...
Assessing the effects of common variation in the FOXP2 gene on human brain structure
FOXP2 imaging genetics language transcription factor MRI brain anatomy VBM
2015/5/5
The FOXP2 transcription factor is one of the most well-known genes to have been implicated in developmental speech and language disorders. Rare mutations disrupting the function of this gene have been...
Patterns of Gray Matter Abnormalities in Schizophrenia Based on an International Mega-analysis
independent component analysis schizophrenia source-based morphometry symptoms voxel-based morphometry
2015/5/5
Analyses of gray matter concentration (GMC) deficits in patients with schizophrenia (Sz) have identified robust changes throughout the cortex. We assessed the relationships between diagnosis, overall ...
Measurement and Genetics of Human Subcortical and Hippocampal Asymmetries in Large Datasets
brain lateralization asymmetry magnetic resonance imaging genetics genome-wide association scan caudate nucleus volumetry subcortical
2015/5/5
Functional and anatomical asymmetries are prevalent features of the human brain, linked to gender, handedness, and cognition. However, little is known about the neurodevelopmental processes involved. ...
Nodes and networks in the neural architecture for language: Broca’s region and beyond
Nodes networks neural architecture Broca’s region and beyond
2015/5/5
Current views on the neurobiological underpinnings oflanguage are discussed that deviate in a number of ways from the classical Wernicke–Lichtheim–Geschwind model. More areas than Broca’s and Wernicke...
Differences in cerebral cortical anatomy of left- and right-handers
MRI handedness cortical surface area brain asymmetry FreeSurfer
2015/5/5
The left and right sides of the human brain are specialized for different kinds of information processing, and much of our cognition is lateralized to an extent toward one side or the other. Handednes...
A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137
direct molecular link autism candidate gene RORa the schizophrenia candidate MIR137
2015/5/5
Retinoic acid-related orphan receptor alpha gene (RORa) and the microRNA MIR137 have both recently been identified as novel candidate genes for neuropsychiatric disorders. RORa encodes a ligand-depend...